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Archive | June, 2015

CRISPR/Cas9 zebrafish

Zebrafish and PCR confirm feasibility of high-throughput editing

CRISPR/Cas9 genome editing is widely used as a tool in genetic studies. Researchers looking at zebrafish have combined this technique with the polymerase chain reaction (PCR) to understand more about the functions of genes in humans. The research is published in Genome Research. CRISPR (clustered, regularly interspaced, short palindromic repeat) describes a pattern of DNA […]

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Introducing SEPSIS-xxpress

SEPSIS-xxpress is BJS Biotechnologies’ rapid POC (point of care) sepsis testing system in development as part of a London-based consortium. The new system combines BJS’s experience in sample preparation, automation and real-time PCR with Brunel University London’s microfluidic engineering skills, while St Georges, University of London, will run clinical trials. With an estimated 25 million annual […]

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Notes on sepsis

Sepsis (blood poisoning) is a life threatening illness reflecting the body’s release of inflammatory cytokines in response to the presence of bacterial and/or fungal pathogens in the bloodstream. Sepsis is the leading cause of death in US hospitals. Mortality from sepsis increases at a rate of 8% for every hour that a patient is not receiving […]

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Scientists use PCR to confirm the impact of malaria in pregnancy

Low-level Plasmodium falciparum infections may not cause full-blown malaria symptoms, but they could still affect pregnant women. Researchers at the Institut de recherche pour le développement (IRD; Institute for Development Research) and the Centre d’Étude et de Recherche sur le Paludisme Associé à la Grossesse et l’Enfance (CERPAGE; Centre for Study and Research on Pregnancy-Associated […]

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